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A Novel “Off-On” Fluorescent Probe Based on Carbon Nitride Nanoribbons for the Detection of Citrate Anion and Live Cell Imaging

A novel fluorescent “off-on” probe based on carbon nitride (C(3)N(4)) nanoribbons was developed for citrate anion (C(6)H(5)O(7)(3−)) detection. The fluorescence of C(3)N(4) nanoribbons can be quenched by Cu(2+) and then recovered by the addition of C(6)H(5)O(7)(3−), because the chelation between C(6...

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Autores principales: Hu, Yanling, Yang, Dongliang, Yang, Chen, Feng, Ning, Shao, Zhouwei, Zhang, Lei, Wang, Xiaodong, Weng, Lixing, Luo, Zhimin, Wang, Lianhui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5948658/
https://www.ncbi.nlm.nih.gov/pubmed/29641452
http://dx.doi.org/10.3390/s18041163
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author Hu, Yanling
Yang, Dongliang
Yang, Chen
Feng, Ning
Shao, Zhouwei
Zhang, Lei
Wang, Xiaodong
Weng, Lixing
Luo, Zhimin
Wang, Lianhui
author_facet Hu, Yanling
Yang, Dongliang
Yang, Chen
Feng, Ning
Shao, Zhouwei
Zhang, Lei
Wang, Xiaodong
Weng, Lixing
Luo, Zhimin
Wang, Lianhui
author_sort Hu, Yanling
collection PubMed
description A novel fluorescent “off-on” probe based on carbon nitride (C(3)N(4)) nanoribbons was developed for citrate anion (C(6)H(5)O(7)(3−)) detection. The fluorescence of C(3)N(4) nanoribbons can be quenched by Cu(2+) and then recovered by the addition of C(6)H(5)O(7)(3−), because the chelation between C(6)H(5)O(7)(3−) and Cu(2+) blocks the electron transfer between Cu(2+) and C(3)N(4) nanoribbons. The turn-on fluorescent sensor using this fluorescent “off-on” probe can detect C(6)H(5)O(7)(3−) rapidly and selectively, showing a wide detection linear range (1~400 μM) and a low detection limit (0.78 μM) in aqueous solutions. Importantly, this C(3)N(4) nanoribbon-based “off-on” probe exhibits good biocompatibility and can be used as fluorescent visualizer for exogenous C(6)H(5)O(7)(3−) in HeLa cells.
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spelling pubmed-59486582018-05-17 A Novel “Off-On” Fluorescent Probe Based on Carbon Nitride Nanoribbons for the Detection of Citrate Anion and Live Cell Imaging Hu, Yanling Yang, Dongliang Yang, Chen Feng, Ning Shao, Zhouwei Zhang, Lei Wang, Xiaodong Weng, Lixing Luo, Zhimin Wang, Lianhui Sensors (Basel) Article A novel fluorescent “off-on” probe based on carbon nitride (C(3)N(4)) nanoribbons was developed for citrate anion (C(6)H(5)O(7)(3−)) detection. The fluorescence of C(3)N(4) nanoribbons can be quenched by Cu(2+) and then recovered by the addition of C(6)H(5)O(7)(3−), because the chelation between C(6)H(5)O(7)(3−) and Cu(2+) blocks the electron transfer between Cu(2+) and C(3)N(4) nanoribbons. The turn-on fluorescent sensor using this fluorescent “off-on” probe can detect C(6)H(5)O(7)(3−) rapidly and selectively, showing a wide detection linear range (1~400 μM) and a low detection limit (0.78 μM) in aqueous solutions. Importantly, this C(3)N(4) nanoribbon-based “off-on” probe exhibits good biocompatibility and can be used as fluorescent visualizer for exogenous C(6)H(5)O(7)(3−) in HeLa cells. MDPI 2018-04-11 /pmc/articles/PMC5948658/ /pubmed/29641452 http://dx.doi.org/10.3390/s18041163 Text en © 2018 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Hu, Yanling
Yang, Dongliang
Yang, Chen
Feng, Ning
Shao, Zhouwei
Zhang, Lei
Wang, Xiaodong
Weng, Lixing
Luo, Zhimin
Wang, Lianhui
A Novel “Off-On” Fluorescent Probe Based on Carbon Nitride Nanoribbons for the Detection of Citrate Anion and Live Cell Imaging
title A Novel “Off-On” Fluorescent Probe Based on Carbon Nitride Nanoribbons for the Detection of Citrate Anion and Live Cell Imaging
title_full A Novel “Off-On” Fluorescent Probe Based on Carbon Nitride Nanoribbons for the Detection of Citrate Anion and Live Cell Imaging
title_fullStr A Novel “Off-On” Fluorescent Probe Based on Carbon Nitride Nanoribbons for the Detection of Citrate Anion and Live Cell Imaging
title_full_unstemmed A Novel “Off-On” Fluorescent Probe Based on Carbon Nitride Nanoribbons for the Detection of Citrate Anion and Live Cell Imaging
title_short A Novel “Off-On” Fluorescent Probe Based on Carbon Nitride Nanoribbons for the Detection of Citrate Anion and Live Cell Imaging
title_sort novel “off-on” fluorescent probe based on carbon nitride nanoribbons for the detection of citrate anion and live cell imaging
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5948658/
https://www.ncbi.nlm.nih.gov/pubmed/29641452
http://dx.doi.org/10.3390/s18041163
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