NADPH oxidases as potential pharmacological targets against increased seizure susceptibility after systemic inflammation

BACKGROUND: Systemic inflammation associated with sepsis can induce neuronal hyperexcitability, leading to enhanced seizure predisposition and occurrence. Brain microglia are rapidly activated in response to systemic inflammation and, in this activated state, release multiple cytokines and signaling...

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Detalles Bibliográficos
Autores principales: Huang, Wan-Yu, Lin, Shankung, Chen, Hsuan-Ying, Chen, Ya-Ping, Chen, Ting-Yu, Hsu, Kuei-Sen, Wu, Hung-Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5948699/
https://www.ncbi.nlm.nih.gov/pubmed/29753328
http://dx.doi.org/10.1186/s12974-018-1186-5

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