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Antiproliferative and apoptotic effect of LY2090314, a GSK-3 inhibitor, in neuroblastoma in vitro

BACKGROUND: Neuroblastoma (NB) is a devastating disease. Despite recent advances in the treatment of NB, about 60% of high-risk NB will have relapse and therefore long-term event free survival is very minimal. We have reported that targeting glycogen synthase kinase-3 (GSK-3) may be a potential stra...

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Detalles Bibliográficos
Autores principales:	Kunnimalaiyaan, Selvi, Schwartz, Victoriana K., Jackson, Iris Alao, Clark Gamblin, T., Kunnimalaiyaan, Muthusamy
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2018
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5948712/ https://www.ncbi.nlm.nih.gov/pubmed/29751783 http://dx.doi.org/10.1186/s12885-018-4474-7

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