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Generation of three-dimensional human neuronal cultures: application to modeling CNS viral infections

BACKGROUND: A variety of neurological disorders including neurodegenerative diseases and infection by neurotropic viruses can cause structural and functional changes in the central nervous system (CNS), resulting in long-term neurological sequelae. An improved understanding of the pathogenesis of th...

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Detalles Bibliográficos
Autores principales: D’Aiuto, Leonardo, Naciri, Jennifer, Radio, Nicholas, Tekur, Sesha, Clayton, Dennis, Apodaca, Gerard, Di Maio, Roberto, Zhi, Yun, Dimitrion, Peter, Piazza, Paolo, Demers, Matthew, Wood, Joel, Chu, Charleen, Callio, Jason, McClain, Lora, Yolken, Robert, McNulty, James, Kinchington, Paul, Bloom, David, Nimgaonkar, Vishwajit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5948884/
https://www.ncbi.nlm.nih.gov/pubmed/29751846
http://dx.doi.org/10.1186/s13287-018-0881-6