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Inferring genetic connectivity in real populations, exemplified by coastal and oceanic Atlantic cod
Genetic data are commonly used to estimate connectivity between putative populations, but translating them to demographic dispersal rates is complicated. Theoretical equations that infer a migration rate based on the genetic estimator F(ST), such as Wright’s equation, F(ST) ≈ 1/(4N(e)m + 1), make as...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5948993/ https://www.ncbi.nlm.nih.gov/pubmed/29674450 http://dx.doi.org/10.1073/pnas.1800096115 |
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author | Spies, Ingrid Hauser, Lorenz Jorde, Per Erik Knutsen, Halvor Punt, André E. Rogers, Lauren A. Stenseth, Nils Chr. |
author_facet | Spies, Ingrid Hauser, Lorenz Jorde, Per Erik Knutsen, Halvor Punt, André E. Rogers, Lauren A. Stenseth, Nils Chr. |
author_sort | Spies, Ingrid |
collection | PubMed |
description | Genetic data are commonly used to estimate connectivity between putative populations, but translating them to demographic dispersal rates is complicated. Theoretical equations that infer a migration rate based on the genetic estimator F(ST), such as Wright’s equation, F(ST) ≈ 1/(4N(e)m + 1), make assumptions that do not apply to most real populations. How complexities inherent to real populations affect migration was exemplified by Atlantic cod in the North Sea and Skagerrak and was examined within an age-structured model that incorporated genetic markers. Migration was determined under various scenarios by varying the number of simulated migrants until the mean simulated level of genetic differentiation matched a fixed level of genetic differentiation equal to empirical estimates. Parameters that decreased the N(e)/N(t) ratio (where N(e) is the effective and N(t) is the total population size), such as high fishing mortality and high fishing gear selectivity, increased the number of migrants required to achieve empirical levels of genetic differentiation. Higher maturity-at-age and lower selectivity increased N(e)/N(t) and decreased migration when genetic differentiation was fixed. Changes in natural mortality, fishing gear selectivity, and maturity-at-age within expected limits had a moderate effect on migration when genetic differentiation was held constant. Changes in population size had the greatest effect on the number of migrants to achieve fixed levels of F(ST), particularly when genetic differentiation was low, F(ST) ≈ 10(−3). Highly variable migration patterns, compared with constant migration, resulted in higher variance in genetic differentiation and higher extreme values. Results are compared with and provide insight into the use of theoretical equations to estimate migration among real populations. |
format | Online Article Text |
id | pubmed-5948993 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2018 |
publisher | National Academy of Sciences |
record_format | MEDLINE/PubMed |
spelling | pubmed-59489932018-05-14 Inferring genetic connectivity in real populations, exemplified by coastal and oceanic Atlantic cod Spies, Ingrid Hauser, Lorenz Jorde, Per Erik Knutsen, Halvor Punt, André E. Rogers, Lauren A. Stenseth, Nils Chr. Proc Natl Acad Sci U S A Biological Sciences Genetic data are commonly used to estimate connectivity between putative populations, but translating them to demographic dispersal rates is complicated. Theoretical equations that infer a migration rate based on the genetic estimator F(ST), such as Wright’s equation, F(ST) ≈ 1/(4N(e)m + 1), make assumptions that do not apply to most real populations. How complexities inherent to real populations affect migration was exemplified by Atlantic cod in the North Sea and Skagerrak and was examined within an age-structured model that incorporated genetic markers. Migration was determined under various scenarios by varying the number of simulated migrants until the mean simulated level of genetic differentiation matched a fixed level of genetic differentiation equal to empirical estimates. Parameters that decreased the N(e)/N(t) ratio (where N(e) is the effective and N(t) is the total population size), such as high fishing mortality and high fishing gear selectivity, increased the number of migrants required to achieve empirical levels of genetic differentiation. Higher maturity-at-age and lower selectivity increased N(e)/N(t) and decreased migration when genetic differentiation was fixed. Changes in natural mortality, fishing gear selectivity, and maturity-at-age within expected limits had a moderate effect on migration when genetic differentiation was held constant. Changes in population size had the greatest effect on the number of migrants to achieve fixed levels of F(ST), particularly when genetic differentiation was low, F(ST) ≈ 10(−3). Highly variable migration patterns, compared with constant migration, resulted in higher variance in genetic differentiation and higher extreme values. Results are compared with and provide insight into the use of theoretical equations to estimate migration among real populations. National Academy of Sciences 2018-05-08 2018-04-19 /pmc/articles/PMC5948993/ /pubmed/29674450 http://dx.doi.org/10.1073/pnas.1800096115 Text en Copyright © 2018 the Author(s). Published by PNAS. https://creativecommons.org/licenses/by-nc-nd/4.0/ This open access article is distributed under Creative Commons Attribution-NonCommercial-NoDerivatives License 4.0 (CC BY-NC-ND) (https://creativecommons.org/licenses/by-nc-nd/4.0/) . |
spellingShingle | Biological Sciences Spies, Ingrid Hauser, Lorenz Jorde, Per Erik Knutsen, Halvor Punt, André E. Rogers, Lauren A. Stenseth, Nils Chr. Inferring genetic connectivity in real populations, exemplified by coastal and oceanic Atlantic cod |
title | Inferring genetic connectivity in real populations, exemplified by coastal and oceanic Atlantic cod |
title_full | Inferring genetic connectivity in real populations, exemplified by coastal and oceanic Atlantic cod |
title_fullStr | Inferring genetic connectivity in real populations, exemplified by coastal and oceanic Atlantic cod |
title_full_unstemmed | Inferring genetic connectivity in real populations, exemplified by coastal and oceanic Atlantic cod |
title_short | Inferring genetic connectivity in real populations, exemplified by coastal and oceanic Atlantic cod |
title_sort | inferring genetic connectivity in real populations, exemplified by coastal and oceanic atlantic cod |
topic | Biological Sciences |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5948993/ https://www.ncbi.nlm.nih.gov/pubmed/29674450 http://dx.doi.org/10.1073/pnas.1800096115 |
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