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Human γδ T-Cells: From Surface Receptors to the Therapy of High-Risk Leukemias
γδ T lymphocytes are potent effector cells, capable of efficiently killing tumor and leukemia cells. Their activation is mediated by γδ T-cell receptor (TCR) and by activating receptors shared with NK cells (e.g., NKG2D and DNAM-1). γδ T-cell triggering occurs upon interaction with specific ligands,...
Autores principales: | Pistoia, Vito, Tumino, Nicola, Vacca, Paola, Veneziani, Irene, Moretta, Alessandro, Locatelli, Franco, Moretta, Lorenzo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5949323/ https://www.ncbi.nlm.nih.gov/pubmed/29867961 http://dx.doi.org/10.3389/fimmu.2018.00984 |
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