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Langerin(+) CD8α(+) Dendritic Cells Drive Early CD8(+) T Cell Activation and IL-12 Production During Systemic Bacterial Infection
Bloodstream infections induce considerable morbidity, high mortality, and represent a significant burden of cost in health care; however, our understanding of the immune response to bacteremia is incomplete. Langerin(+) CD8α(+) dendritic cells (DCs), residing in the marginal zone of the murine splee...
Autores principales: | Prendergast, Kelly A., Daniels, Naomi J., Petersen, Troels R., Hermans, Ian F., Kirman, Joanna R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5949331/ https://www.ncbi.nlm.nih.gov/pubmed/29867941 http://dx.doi.org/10.3389/fimmu.2018.00953 |
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