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Macrophage Depletion Lowered Blood Pressure and Attenuated Hypertensive Renal Injury and Fibrosis

Monocyte/macrophage recruitment is closely associated with the degree of hypertensive renal injury. We investigated the direct role of macrophages using liposome-encapsulated clodronate (LEC) to deplete monocytes/macrophages in hypertensive renal injury. C57BL/6 mice were treated with a pressor dose...

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Detalles Bibliográficos
Autores principales: Huang, Lei, Wang, Aimei, Hao, Yun, Li, Weihong, Liu, Chang, Yang, Zhihang, Zheng, Feng, Zhou, Ming-Sheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5949360/
https://www.ncbi.nlm.nih.gov/pubmed/29867533
http://dx.doi.org/10.3389/fphys.2018.00473