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NH36 and F3 Antigen-Primed Dendritic Cells Show Preserved Migrating Capabilities and CCR7 Expression and F3 Is Effective in Immunotherapy of Visceral Leishmaniasis
Physical contact between dendritic cells (DCs) and T cell lymphocytes is necessary to trigger the immune cell response. CCL19 and CCL21 chemokines bind to the CCR7 receptor of mature DCs, and of T cells and regulate DCs migration to the white pulp (wp) of the spleen, where they encounter lymphocytes...
Autores principales: | Nico, Dirlei, Martins Almeida, Fernanda, Maria Motta, Juliana, Soares dos Santos Cardoso, Fellipe, Freire-de-Lima, Celio Geraldo, Freire-de-Lima, Leonardo, de Luca, Paula Melo, Maria Blanco Martinez, Ana, Morrot, Alexandre, Palatnik-de-Sousa, Clarisa Beatriz |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5949526/ https://www.ncbi.nlm.nih.gov/pubmed/29867949 http://dx.doi.org/10.3389/fimmu.2018.00967 |
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