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Inhibitory effect of PDGF-BB and serum-stimulated responses in vascular smooth muscle cell proliferation by hinokitiol via up-regulation of p21 and p53
INTRODUCTION: Vascular smooth muscle cell (VSMC) proliferation plays a major role in the progression of vascular diseases. In the present study, we established the efficacy and the mechanisms of action of hinokitiol, a tropolone derivative found in Chamaecyparis taiwanensis, Cupressaceae, in relatio...
Autores principales: | Li, Jiun-Yi, Liu, Chun-Ping, Shiao, Wei-Cheng, Jayakumar, Thanasekaran, Li, Yi-Shin, Chang, Nen-Chung, Huang, Shih-Yi, Hsieh, Cheng-Ying |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Termedia Publishing House
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5949921/ https://www.ncbi.nlm.nih.gov/pubmed/29765446 http://dx.doi.org/10.5114/aoms.2018.75085 |
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