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Effects of hypo-O-GlcNAcylation on Drosophila development

Post-translational modification of serine/threonine residues in nucleocytoplasmic proteins with GlcNAc (O-GlcNAcylation) is an essential regulatory mechanism in many cellular processes. In Drosophila, null mutants of the Polycomb gene O-GlcNAc transferase (OGT; also known as super sex combs (sxc)) d...

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Detalles Bibliográficos
Autores principales: Mariappa, Daniel, Ferenbach, Andrew T., van Aalten, Daan M. F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5950000/
https://www.ncbi.nlm.nih.gov/pubmed/29588363
http://dx.doi.org/10.1074/jbc.RA118.002580

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