Promiscuous activities of heterologous enzymes lead to unintended metabolic rerouting in Saccharomyces cerevisiae engineered to assimilate various sugars from renewable biomass

BACKGROUND: Understanding the global metabolic network, significantly perturbed upon promiscuous activities of foreign enzymes and different carbon sources, is crucial for systematic optimization of metabolic engineering of yeast Saccharomyces cerevisiae. Here, we studied the effects of promiscuous...

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Detalles Bibliográficos
Autores principales: Yun, Eun Ju, Oh, Eun Joong, Liu, Jing-Jing, Yu, Sora, Kim, Dong Hyun, Kwak, Suryang, Kim, Kyoung Heon, Jin, Yong-Su
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5950193/
https://www.ncbi.nlm.nih.gov/pubmed/29785207
http://dx.doi.org/10.1186/s13068-018-1135-7

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