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Modular synthesis of dihydro-isoquinolines: palladium-catalyzed sequential C(sp(2))–H and C(sp(3))–H bond activation

An efficient synthesis of dihydro-isoquinolines via a Pd–catalyzed double C–H bond [a C(sp(2))–H and a C(sp(3))–H bond] activation/annulation (CHAA) reaction is presented. This methodology features a short reaction time, high atom economy (loss of H(2)O only) and the formation of a sterically less f...

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Detalles Bibliográficos
Autores principales:	Liu, Weidong, Yu, Qingzhen, Hu, Le'an, Chen, Zenghua, Huang, Jianhui
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Royal Society of Chemistry 2015
Materias:	Chemistry
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5950195/ https://www.ncbi.nlm.nih.gov/pubmed/29861906 http://dx.doi.org/10.1039/c5sc01482d

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