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Overexpression of dihydrofolate reductase is a factor of poor survival in acute lymphoblastic leukemia

Dihydrofolate reductase (DHFR) has an important function in DNA synthesis and is a target of methotrexate, which is a crucial treatment option for acute lymphoblastic leukemia (ALL). However, the number of studies conducted to date on DHFR expression in childhood ALL is limited. The aim of the prese...

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Detalles Bibliográficos
Autores principales:	Organista-Nava, Jorge, Gómez-Gómez, Yazmín, Illades-Aguiar, Berenice, Rivera-Ramírez, Ana Bertha, Saavedra-Herrera, Mónica Virginia, Leyva-Vázquez, Marco Antonio
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2018
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5950508/ https://www.ncbi.nlm.nih.gov/pubmed/29805575 http://dx.doi.org/10.3892/ol.2018.8429

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