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Cronkhite-Canada syndrome: A case report
Cronkhite-Canada syndrome (CCS) is a rare non-inherited condition characterized by gastrointestinal (GI) hamartomatous polyposis, alopecia, onychodystrophy, hyperpigmentation, weight loss and diarrhea. The etiology is most likely autoimmune and diagnosis is based on patient history, physical examina...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
D.A. Spandidos
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5950510/ https://www.ncbi.nlm.nih.gov/pubmed/29805581 http://dx.doi.org/10.3892/ol.2018.8409 |
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author | Yuan, Wei Tian, Li Ai, Fei-Yan Liu, Shao-Jun Shen, Shou-Rong Wang, Xiao-Yan Liu, Fen |
author_facet | Yuan, Wei Tian, Li Ai, Fei-Yan Liu, Shao-Jun Shen, Shou-Rong Wang, Xiao-Yan Liu, Fen |
author_sort | Yuan, Wei |
collection | PubMed |
description | Cronkhite-Canada syndrome (CCS) is a rare non-inherited condition characterized by gastrointestinal (GI) hamartomatous polyposis, alopecia, onychodystrophy, hyperpigmentation, weight loss and diarrhea. The etiology is most likely autoimmune and diagnosis is based on patient history, physical examination, endoscopic findings of GI polyposis and histology. The disease is very rare; thus far more than 500 cases of CCS have been reported globally. A 58-years-old male with CCS was reported in the present case study. The patient experienced a history of diarrhea and hematochezia for 4 months, with abdominal pain for 1 month and additional nail and toenail loss for half a month. The clinical, endoscopic and histological data confirmed the diagnosis. |
format | Online Article Text |
id | pubmed-5950510 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2018 |
publisher | D.A. Spandidos |
record_format | MEDLINE/PubMed |
spelling | pubmed-59505102018-05-27 Cronkhite-Canada syndrome: A case report Yuan, Wei Tian, Li Ai, Fei-Yan Liu, Shao-Jun Shen, Shou-Rong Wang, Xiao-Yan Liu, Fen Oncol Lett Articles Cronkhite-Canada syndrome (CCS) is a rare non-inherited condition characterized by gastrointestinal (GI) hamartomatous polyposis, alopecia, onychodystrophy, hyperpigmentation, weight loss and diarrhea. The etiology is most likely autoimmune and diagnosis is based on patient history, physical examination, endoscopic findings of GI polyposis and histology. The disease is very rare; thus far more than 500 cases of CCS have been reported globally. A 58-years-old male with CCS was reported in the present case study. The patient experienced a history of diarrhea and hematochezia for 4 months, with abdominal pain for 1 month and additional nail and toenail loss for half a month. The clinical, endoscopic and histological data confirmed the diagnosis. D.A. Spandidos 2018-06 2018-04-02 /pmc/articles/PMC5950510/ /pubmed/29805581 http://dx.doi.org/10.3892/ol.2018.8409 Text en Copyright: © Yuan et al. This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License (https://creativecommons.org/licenses/by-nc-nd/4.0/) , which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made. |
spellingShingle | Articles Yuan, Wei Tian, Li Ai, Fei-Yan Liu, Shao-Jun Shen, Shou-Rong Wang, Xiao-Yan Liu, Fen Cronkhite-Canada syndrome: A case report |
title | Cronkhite-Canada syndrome: A case report |
title_full | Cronkhite-Canada syndrome: A case report |
title_fullStr | Cronkhite-Canada syndrome: A case report |
title_full_unstemmed | Cronkhite-Canada syndrome: A case report |
title_short | Cronkhite-Canada syndrome: A case report |
title_sort | cronkhite-canada syndrome: a case report |
topic | Articles |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5950510/ https://www.ncbi.nlm.nih.gov/pubmed/29805581 http://dx.doi.org/10.3892/ol.2018.8409 |
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