Accelerated model of lupus autoimmunity and vasculopathy driven by toll-like receptor 7/9 imbalance

OBJECTIVES: Activation of endosomal toll-like receptor (TLR)7 or TLR9 has been proposed as a critical step for the initiation and development of SLE. Traditional spontaneous lupus models normally introduce multiple risk alleles, thereby adding additional confounding factors. In the induced lupus mod...

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Detalles Bibliográficos
Autores principales: Liu, Yudong, Seto, Nickie L, Carmona-Rivera, Carmelo, Kaplan, Mariana J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2018
Materias:
Animal Models
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5950641/
https://www.ncbi.nlm.nih.gov/pubmed/29765617
http://dx.doi.org/10.1136/lupus-2018-000259

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5950641/
https://www.ncbi.nlm.nih.gov/pubmed/29765617
http://dx.doi.org/10.1136/lupus-2018-000259

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