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Accelerated model of lupus autoimmunity and vasculopathy driven by toll-like receptor 7/9 imbalance
OBJECTIVES: Activation of endosomal toll-like receptor (TLR)7 or TLR9 has been proposed as a critical step for the initiation and development of SLE. Traditional spontaneous lupus models normally introduce multiple risk alleles, thereby adding additional confounding factors. In the induced lupus mod...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BMJ Publishing Group
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5950641/ https://www.ncbi.nlm.nih.gov/pubmed/29765617 http://dx.doi.org/10.1136/lupus-2018-000259 |