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The Rho-associated kinase inhibitors Y27632 and fasudil promote microglial migration in the spinal cord via the ERK signaling pathway

Rho-associated kinase (ROCK) is a key regulatory protein involved in inflammatory secretion in microglia in the central nervous system. Our previous studies showed that ROCK inhibition enhances phagocytic activity in microglia through the extracellular signal-regulated kinase (ERK) signaling pathway...

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Detalles Bibliográficos
Autores principales: Fu, Pei-Cai, Tang, Rong-Hua, Yu, Zhi-Yuan, Xie, Min-Jie, Wang, Wei, Luo, Xiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5950678/
https://www.ncbi.nlm.nih.gov/pubmed/29722320
http://dx.doi.org/10.4103/1673-5374.230294