Cargando…

The Rho-associated kinase inhibitors Y27632 and fasudil promote microglial migration in the spinal cord via the ERK signaling pathway

Rho-associated kinase (ROCK) is a key regulatory protein involved in inflammatory secretion in microglia in the central nervous system. Our previous studies showed that ROCK inhibition enhances phagocytic activity in microglia through the extracellular signal-regulated kinase (ERK) signaling pathway...

Descripción completa

Detalles Bibliográficos
Autores principales:	Fu, Pei-Cai, Tang, Rong-Hua, Yu, Zhi-Yuan, Xie, Min-Jie, Wang, Wei, Luo, Xiang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Medknow Publications & Media Pvt Ltd 2018
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5950678/ https://www.ncbi.nlm.nih.gov/pubmed/29722320 http://dx.doi.org/10.4103/1673-5374.230294

Ejemplares similares

The Rho-associated kinase inhibitor fasudil can replace Y-27632 for use in human pluripotent stem cell research
por: So, Seongjun, et al.
Publicado: (2020)

Advantages of Rho-associated kinases and their inhibitor fasudil for the treatment of neurodegenerative diseases
por: Wang, Qing, et al.
Publicado: (2022)

Effects of the Rho-Kinase Inhibitor Y-27632 on Extraocular Muscle Surgery in Rabbits
por: Moon, Ji‐Sun, et al.
Publicado: (2017)

Rho‐kinase inhibitor Y‐27632 facilitates the proliferation, migration and pluripotency of human periodontal ligament stem cells
por: Wang, Ting, et al.
Publicado: (2017)

Fasudil, a Rho-Kinase Inhibitor, Attenuates Bleomycin-Induced Pulmonary Fibrosis in Mice
por: Jiang, Chunguo, et al.
Publicado: (2012)

The role of Rho/Rho-kinase pathway and the neuroprotective effects of fasudil in chronic cerebral ischemia
por: Yan, Ya-yun, et al.
Publicado: (2015)

Rho-associated kinase inhibitor Y-27632 promotes survival of cynomolgus monkey embryonic stem cells
por: Takehara, Toshiyuki, et al.
Publicado: (2008)

The role of Rho-associated kinase inhibitor, Y-27632 on primary culture of ovine spermatogonial stem cells
por: Emamdoust, Fatemeh, et al.
Publicado: (2022)

Rho Kinase Inhibition by Fasudil Ameliorates Diabetes-Induced Microvascular Damage
por: Arita, Ryoichi, et al.
Publicado: (2009)

The non-selective Rho-kinase inhibitors Y-27632 and Y-33075 decrease contraction but increase migration in murine and human hepatic stellate cells
por: Bachtler, Nadine, et al.
Publicado: (2023)

Rho kinase inhibitors Y27632 and H1152 augment neurite extension in the presence of cultured Schwann cells
por: Fuentes, Erick O, et al.
Publicado: (2008)

A selective inhibitor of the Rho kinase pathway, Y-27632, and its influence on wound healing in the corneal stroma
por: Yamamoto, Mayumi, et al.
Publicado: (2012)

Rho-Associated Kinase Inhibitor (Y-27632) Attenuates Doxorubicin-Induced Apoptosis of Human Cardiac Stem Cells
por: Kan, Lijuan, et al.
Publicado: (2015)

Prolonging culture of primary human keratinocytes isolated from suction blisters with the Rho kinase inhibitor Y-27632
por: Anderson, Erik D., et al.
Publicado: (2018)

Effects of Rho-Associated Kinase (Rock) Inhibitors (Alternative to Y-27632) on Primary Human Corneal Endothelial Cells
por: Peh, Gary S. L., et al.
Publicado: (2023)

Correction: Rho Kinase Inhibitor Y27632 Improves Recovery After Spinal Cord Injury by Shifting Astrocyte Phenotype and Morphology via the ROCK/NF-?B/C3 Pathway
por: Zhang, Yongyuan, et al.
Publicado: (2022)

Rho Kinase Inhibitor Y27632 Improves Recovery After Spinal Cord Injury by Shifting Astrocyte Phenotype and Morphology via the ROCK/NF-κB/C3 Pathway
por: Zhang, Yongyuan, et al.
Publicado: (2022)

Phenotypes of trypsin- and collagenase-prepared bovine corneal endothelial cells in the presence of a selective Rho kinase inhibitor, Y-27632
por: Su, Chien-Chia, et al.
Publicado: (2015)

Fasudil, an inhibitor of Rho-associated coiled-coil kinase, improves cognitive impairments induced by smoke exposure
por: Xueyang, Deng, et al.
Publicado: (2016)

Inhibition of RhoA/Rho kinase signaling pathway by fasudil protects against kainic acid‐induced neurite injury
por: Xiang, Yingchun, et al.
Publicado: (2021)

The rho kinase inhibitor Y-27632 improves motor performance in male SOD1(G93A) mice
por: Günther, René, et al.
Publicado: (2014)

An in vitro study of scarring formation mediated by human Tenon fibroblasts: Effect of Y‐27632, a Rho kinase inhibitor
por: Ibrahim, Diah Gemala, et al.
Publicado: (2019)

Combination of fasudil and celecoxib promotes the recovery of injured spinal cord in rats better than celecoxib or fasudil alone
por: Hou, Xiao-lin, et al.
Publicado: (2015)

Influence of Rho/ROCK inhibitor Y-27632 on proliferation of equine mesenchymal stromal cells
por: Melzer, Michaela, et al.
Publicado: (2023)

RhoA/Rho kinase in spinal cord injury
por: Wu, Xiangbing, et al.
Publicado: (2016)

Fasudil, a Rho-kinase inhibitor, prevents intima-media thickening in a partially ligated carotid artery mouse model: Effects of fasudil in flow-induced vascular remodeling
por: Zhang, Xiangyu, et al.
Publicado: (2015)

The effects of Rho-associated kinase inhibitor Y-27632 on primary human corneal endothelial cells propagated using a dual media approach
por: Peh, Gary S. L., et al.
Publicado: (2015)

Inhibition of Rho-Kinase by Fasudil Suppresses Formation and Progression of Experimental Abdominal Aortic Aneurysms
por: Peng, Chen, et al.
Publicado: (2013)

Inhalation of the Rho-kinase inhibitor Y-27632 reverses allergen-induced airway hyperresponsiveness after the early and late asthmatic reaction
por: Schaafsma, Dedmer, et al.
Publicado: (2006)

A Rho Kinase (ROCK) Inhibitor, Y-27632, Inhibits the Dissociation-Induced Cell Death of Salivary Gland Stem Cells
por: Kim, Kichul, et al.
Publicado: (2021)

Y‐27632, an Inhibitor of Rho‐associated Protein Kinase, Suppresses Tumor Cell Invasion via Regulation of Focal Adhesion and Focal Adhesion Kinase
por: Imamura, Fumio, et al.
Publicado: (2000)

Increased Liver Uptake and Reduced Hepatic Stellate Cell Activation with a Cell-Specific Conjugate of the Rho-kinase Inhibitor Y27632
por: van Beuge, Marike Marjolijn, et al.
Publicado: (2011)

Rho-kinase inhibitor Y-27632 and hypoxia synergistically enhance chondrocytic phenotype and modify S100 protein profiles in human chondrosarcoma cells
por: Piltti, Juha, et al.
Publicado: (2017)

Retraction: Inhibition of Rho-Kinase by Fasudil Suppresses Formation and Progression of Experimental Abdominal Aortic Aneurysms
por: Peng, Chen, et al.
Publicado: (2014)

Suppression of the Rho/Rho-Kinase Pathway and Prevention of Cerebral Vasospasm by Combination Treatment with Statin and Fasudil After Subarachnoid Hemorrhage in Rabbit
por: Naraoka, Masato, et al.
Publicado: (2013)

Establishment of an Efficient Primary Culture System for Human Hair Follicle Stem Cells Using the Rho-Associated Protein Kinase Inhibitor Y-27632
por: Wen, Lihong, et al.
Publicado: (2021)

Fasudil Promotes BMSC Migration via Activating the MAPK Signaling Pathway and Application in a Model of Spinal Cord Injury
por: Zhan, Jiheng, et al.
Publicado: (2018)

The Rho/Rho-associated protein kinase inhibitor fasudil in the protection of endothelial cells against advanced glycation end products through the nuclear factor κB pathway
por: LU, YUYAN, et al.
Publicado: (2013)

Protective Effects of Intravitreal Injection of the Rho-Kinase Inhibitor Y-27632 in a Rodent Model of Nonarteritic Anterior Ischemic Optic Neuropathy (rAION)
por: Yi, Zuohuizi, et al.
Publicado: (2020)

Effects of Y-27632, a Rho-associated Kinase Inhibitor, on Human Corneal Endothelial Cells Cultured by Isolating Human Corneal Endothelial Progenitor Cells
por: Shin, Haeeun, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_n0o0u5rsovcti6p9dd3uuf9li2