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LNA-enhanced DNA FIT-probes for multicolour RNA imaging

The simultaneous imaging of different RNA molecules in homogeneous solution is a challenge and requires optimisation to enable unambiguous staining of intracellular RNA targets. Our approach relies on single dye forced intercalation (FIT) probes, in which a visco-sensitive reporter of the thiazole o...

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Detalles Bibliográficos
Autores principales:	Hövelmann, F., Gaspar, I., Chamiolo, J., Kasper, M., Steffen, J., Ephrussi, A., Seitz, O.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Royal Society of Chemistry 2016
Materias:	Chemistry
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5950760/ https://www.ncbi.nlm.nih.gov/pubmed/29861973 http://dx.doi.org/10.1039/c5sc03053f

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