Cargando…

Plant Lineage-Specific Amplification of Transcription Factor Binding Motifs by Miniature Inverted-Repeat Transposable Elements (MITEs)

Transposable elements are one of the main drivers of plant genome evolution. Transposon insertions can modify the gene coding capacity or the regulation of their expression, the latter being a more subtle effect, and therefore particularly useful for evolution. Transposons have been show to contain...

Descripción completa

Detalles Bibliográficos
Autores principales: Morata, Jordi, Marín, Fatima, Payet, Jordi, Casacuberta, Josep M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5950925/
https://www.ncbi.nlm.nih.gov/pubmed/29659815
http://dx.doi.org/10.1093/gbe/evy073
_version_ 1783322960579264512
author Morata, Jordi
Marín, Fatima
Payet, Jordi
Casacuberta, Josep M
author_facet Morata, Jordi
Marín, Fatima
Payet, Jordi
Casacuberta, Josep M
author_sort Morata, Jordi
collection PubMed
description Transposable elements are one of the main drivers of plant genome evolution. Transposon insertions can modify the gene coding capacity or the regulation of their expression, the latter being a more subtle effect, and therefore particularly useful for evolution. Transposons have been show to contain transcription factor binding sites that can be mobilized upon transposition with the potential to integrate new genes into transcriptional networks. Miniature inverted-repeat transposable elements (MITEs) are a type of noncoding DNA transposons that could be particularly suited as a vector to mobilize transcription factor binding sites and modify transcriptional networks during evolution. MITEs are small in comparison to other transposons and can be excised, which should make them less mutagenic when inserting into promoters. On the other hand, in spite of their cut-and-paste mechanisms of transposition, they can reach very high copy numbers in genomes. We have previously shown that MITEs have amplified and redistributed the binding motif of the E2F transcription factor in different Brassicas. Here, we show that MITEs have amplified and mobilized the binding motifs of the bZIP60 and PIF3 transcription factors in peach and Prunus mume, and the TCP15/23 binding motif in tomato. Our results suggest that MITEs could have rewired new genes into transcriptional regulatory networks that are responsible for important adaptive responses and breeding traits in plants, such as stress responses, flowering time, or fruit ripening. The results presented here therefore suggest a general impact of MITEs in the evolution of transcriptional regulatory networks in plants.
format Online
Article
Text
id pubmed-5950925
institution National Center for Biotechnology Information
language English
publishDate 2018
publisher Oxford University Press
record_format MEDLINE/PubMed
spelling pubmed-59509252018-05-16 Plant Lineage-Specific Amplification of Transcription Factor Binding Motifs by Miniature Inverted-Repeat Transposable Elements (MITEs) Morata, Jordi Marín, Fatima Payet, Jordi Casacuberta, Josep M Genome Biol Evol Research Article Transposable elements are one of the main drivers of plant genome evolution. Transposon insertions can modify the gene coding capacity or the regulation of their expression, the latter being a more subtle effect, and therefore particularly useful for evolution. Transposons have been show to contain transcription factor binding sites that can be mobilized upon transposition with the potential to integrate new genes into transcriptional networks. Miniature inverted-repeat transposable elements (MITEs) are a type of noncoding DNA transposons that could be particularly suited as a vector to mobilize transcription factor binding sites and modify transcriptional networks during evolution. MITEs are small in comparison to other transposons and can be excised, which should make them less mutagenic when inserting into promoters. On the other hand, in spite of their cut-and-paste mechanisms of transposition, they can reach very high copy numbers in genomes. We have previously shown that MITEs have amplified and redistributed the binding motif of the E2F transcription factor in different Brassicas. Here, we show that MITEs have amplified and mobilized the binding motifs of the bZIP60 and PIF3 transcription factors in peach and Prunus mume, and the TCP15/23 binding motif in tomato. Our results suggest that MITEs could have rewired new genes into transcriptional regulatory networks that are responsible for important adaptive responses and breeding traits in plants, such as stress responses, flowering time, or fruit ripening. The results presented here therefore suggest a general impact of MITEs in the evolution of transcriptional regulatory networks in plants. Oxford University Press 2018-04-05 /pmc/articles/PMC5950925/ /pubmed/29659815 http://dx.doi.org/10.1093/gbe/evy073 Text en © The Author(s) 2018. Published by Oxford University Press on behalf of the Society for Molecular Biology and Evolution. http://creativecommons.org/licenses/by-nc/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.com
spellingShingle Research Article
Morata, Jordi
Marín, Fatima
Payet, Jordi
Casacuberta, Josep M
Plant Lineage-Specific Amplification of Transcription Factor Binding Motifs by Miniature Inverted-Repeat Transposable Elements (MITEs)
title Plant Lineage-Specific Amplification of Transcription Factor Binding Motifs by Miniature Inverted-Repeat Transposable Elements (MITEs)
title_full Plant Lineage-Specific Amplification of Transcription Factor Binding Motifs by Miniature Inverted-Repeat Transposable Elements (MITEs)
title_fullStr Plant Lineage-Specific Amplification of Transcription Factor Binding Motifs by Miniature Inverted-Repeat Transposable Elements (MITEs)
title_full_unstemmed Plant Lineage-Specific Amplification of Transcription Factor Binding Motifs by Miniature Inverted-Repeat Transposable Elements (MITEs)
title_short Plant Lineage-Specific Amplification of Transcription Factor Binding Motifs by Miniature Inverted-Repeat Transposable Elements (MITEs)
title_sort plant lineage-specific amplification of transcription factor binding motifs by miniature inverted-repeat transposable elements (mites)
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5950925/
https://www.ncbi.nlm.nih.gov/pubmed/29659815
http://dx.doi.org/10.1093/gbe/evy073
work_keys_str_mv AT moratajordi plantlineagespecificamplificationoftranscriptionfactorbindingmotifsbyminiatureinvertedrepeattransposableelementsmites
AT marinfatima plantlineagespecificamplificationoftranscriptionfactorbindingmotifsbyminiatureinvertedrepeattransposableelementsmites
AT payetjordi plantlineagespecificamplificationoftranscriptionfactorbindingmotifsbyminiatureinvertedrepeattransposableelementsmites
AT casacubertajosepm plantlineagespecificamplificationoftranscriptionfactorbindingmotifsbyminiatureinvertedrepeattransposableelementsmites