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Long-term Outcome of a Fissurectomy: A Prospective Single-Arm Study of 50 Operations out of 349 Initial Patients

PURPOSE: The surgical standard of care for patients with chronic anal fissure is still disputed. We aimed to assess the natural course of idiopathic anal fissure and the long-term outcome of a fissurectomy as a surgical treatment. METHODS: All consecutive patients referred to a single expert practit...

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Autores principales: Zeitoun, Jean-David, Blanchard, Pierre, Fathallah, Nadia, Benfredj, Paul, Lemarchand, Nicolas, de Parades, Vincent
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society of Coloproctology 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5951090/
https://www.ncbi.nlm.nih.gov/pubmed/29742858
http://dx.doi.org/10.3393/ac.2017.06.12
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author Zeitoun, Jean-David
Blanchard, Pierre
Fathallah, Nadia
Benfredj, Paul
Lemarchand, Nicolas
de Parades, Vincent
author_facet Zeitoun, Jean-David
Blanchard, Pierre
Fathallah, Nadia
Benfredj, Paul
Lemarchand, Nicolas
de Parades, Vincent
author_sort Zeitoun, Jean-David
collection PubMed
description PURPOSE: The surgical standard of care for patients with chronic anal fissure is still disputed. We aimed to assess the natural course of idiopathic anal fissure and the long-term outcome of a fissurectomy as a surgical treatment. METHODS: All consecutive patients referred to a single expert practitioner in a tertiary centre were primarily included. A fissurectomy was proposed in cases of refractory symptoms after 4 to 6 weeks of standard medical management. Only patients with idiopathic and noninfected anal fissures were included in this second subsample to undergo surgery. Conventional postoperative management was prescribed for all patients who had undergone surgery. The main outcome measures were the success rate (defined as a combination of wound healing and relief of pain) and postoperative anal continence. RESULTS: Three hundred forty-nine patients were primarily recruited. Fifty patients finally underwent surgery for an idiopathic and noninfected fissure. Among them, 47 (94%) were cured at the end of primary follow-up, and 44 of the 47 (93.6%) could be confirmed as being sustainably cured in the longer-term follow-up. The mean time of complete healing was 10.3 weeks (range, 5.7–36.4 weeks). All patients were free of pain at weeks 42. The continence score after surgery was not statistically different from the preoperative score. CONCLUSION: A fissurectomy for the treatment of patients with an idiopathic noninfected fissure is associated with rapid pain relief and a high success rate even though complete healing may often be delayed. Moreover, it appears to have no adverse effect on continence.
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spelling pubmed-59510902018-05-16 Long-term Outcome of a Fissurectomy: A Prospective Single-Arm Study of 50 Operations out of 349 Initial Patients Zeitoun, Jean-David Blanchard, Pierre Fathallah, Nadia Benfredj, Paul Lemarchand, Nicolas de Parades, Vincent Ann Coloproctol Original Article PURPOSE: The surgical standard of care for patients with chronic anal fissure is still disputed. We aimed to assess the natural course of idiopathic anal fissure and the long-term outcome of a fissurectomy as a surgical treatment. METHODS: All consecutive patients referred to a single expert practitioner in a tertiary centre were primarily included. A fissurectomy was proposed in cases of refractory symptoms after 4 to 6 weeks of standard medical management. Only patients with idiopathic and noninfected anal fissures were included in this second subsample to undergo surgery. Conventional postoperative management was prescribed for all patients who had undergone surgery. The main outcome measures were the success rate (defined as a combination of wound healing and relief of pain) and postoperative anal continence. RESULTS: Three hundred forty-nine patients were primarily recruited. Fifty patients finally underwent surgery for an idiopathic and noninfected fissure. Among them, 47 (94%) were cured at the end of primary follow-up, and 44 of the 47 (93.6%) could be confirmed as being sustainably cured in the longer-term follow-up. The mean time of complete healing was 10.3 weeks (range, 5.7–36.4 weeks). All patients were free of pain at weeks 42. The continence score after surgery was not statistically different from the preoperative score. CONCLUSION: A fissurectomy for the treatment of patients with an idiopathic noninfected fissure is associated with rapid pain relief and a high success rate even though complete healing may often be delayed. Moreover, it appears to have no adverse effect on continence. Korean Society of Coloproctology 2018-04 2018-04-30 /pmc/articles/PMC5951090/ /pubmed/29742858 http://dx.doi.org/10.3393/ac.2017.06.12 Text en © 2018 The Korean Society of Coloproctology This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Article
Zeitoun, Jean-David
Blanchard, Pierre
Fathallah, Nadia
Benfredj, Paul
Lemarchand, Nicolas
de Parades, Vincent
Long-term Outcome of a Fissurectomy: A Prospective Single-Arm Study of 50 Operations out of 349 Initial Patients
title Long-term Outcome of a Fissurectomy: A Prospective Single-Arm Study of 50 Operations out of 349 Initial Patients
title_full Long-term Outcome of a Fissurectomy: A Prospective Single-Arm Study of 50 Operations out of 349 Initial Patients
title_fullStr Long-term Outcome of a Fissurectomy: A Prospective Single-Arm Study of 50 Operations out of 349 Initial Patients
title_full_unstemmed Long-term Outcome of a Fissurectomy: A Prospective Single-Arm Study of 50 Operations out of 349 Initial Patients
title_short Long-term Outcome of a Fissurectomy: A Prospective Single-Arm Study of 50 Operations out of 349 Initial Patients
title_sort long-term outcome of a fissurectomy: a prospective single-arm study of 50 operations out of 349 initial patients
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5951090/
https://www.ncbi.nlm.nih.gov/pubmed/29742858
http://dx.doi.org/10.3393/ac.2017.06.12
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