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LincRNA-1614 coordinates Sox2/PRC2-mediated repression of developmental genes in pluripotency maintenance
Large-intergenic noncoding RNAs (lincRNAs) cooperate with core transcription factors to coordinate the pluripotency network of embryonic stem cells. The mechanisms by which lincRNAs affect chromatin structure and gene transcription remain mostly unknown. Here, we identified that a lincRNA (linc1614)...
Autores principales: | Guo, Xudong, Wang, Zikang, Lu, Chenqi, Hong, Wujun, Wang, Guiying, Xu, Yanxin, Liu, Zhongmin, Kang, Jiuhong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5951109/ https://www.ncbi.nlm.nih.gov/pubmed/28992244 http://dx.doi.org/10.1093/jmcb/mjx041 |
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