Protein delivery nanosystem of six-arm copolymer poly(ε-caprolactone)–poly(ethylene glycol) for long-term sustained release

BACKGROUND: To address the issue of delivery of proteins, a six-arm copolymer, six-arm poly (ε-caprolactone)–poly(ethylene glycol) (6S-PCL-PEG), was synthesized by a simple two-step reaction. Thereafter, the application of 6S-PCL-PEG as a protein carrier was evaluated. MATERIALS AND METHODS: A six-a...

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Detalles Bibliográficos
Autores principales: Duan, Jianwei, Liu, Chao, Liang, Xiaoyu, Li, Xuanling, Chen, Youlu, Chen, Zuoguan, Wang, Xiaoli, Kong, Deling, Li, Yongjun, Yang, Jing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2018
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5951147/
https://www.ncbi.nlm.nih.gov/pubmed/29780245
http://dx.doi.org/10.2147/IJN.S161006

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