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Expression variation and covariation impair analog and enable binary signaling control

Due to noise in the synthesis and degradation of proteins, the concentrations of individual vertebrate signaling proteins were estimated to vary with a coefficient of variation (CV) of approximately 25% between cells. Such high variation is beneficial for population‐level regulation of cell function...

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Detalles Bibliográficos
Autores principales: Kovary, Kyle M, Taylor, Brooks, Zhao, Michael L, Teruel, Mary N
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5951153/
https://www.ncbi.nlm.nih.gov/pubmed/29759982
http://dx.doi.org/10.15252/msb.20177997

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