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Retinopathy and Mortality

OBJECTIVE. We evaluated the specific association between retinopathy and all-cause mortality among a national sample of the broader U.S. adult population. METHODS. Data from the 2005–2008 National Health and Nutrition Examination Survey were used to identify 4,777 adults with complete data regarding...

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Autores principales: Frith, Emily, Loprinzi, Paul D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Diabetes Association 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5951238/
https://www.ncbi.nlm.nih.gov/pubmed/29773939
http://dx.doi.org/10.2337/ds17-0010
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author Frith, Emily
Loprinzi, Paul D.
author_facet Frith, Emily
Loprinzi, Paul D.
author_sort Frith, Emily
collection PubMed
description OBJECTIVE. We evaluated the specific association between retinopathy and all-cause mortality among a national sample of the broader U.S. adult population. METHODS. Data from the 2005–2008 National Health and Nutrition Examination Survey were used to identify 4,777 adults with complete data regarding screening for nonproliferative retinopathy using Early Treatment Diabetic Retinopathy Study grading criteria, as well as objective retinal imaging assessments using the Canon Non-Mydriatic Retinal Camera CR6-45NM. Participants were not included if they had been diagnosed with coronary artery disease, congestive heart failure, heart attack, or stroke at the baseline assessment. RESULTS. Both mild and moderate/severe retinopathy were associated with increased all-cause mortality risk in unadjusted and adjusted models. In the adjusted model, and when compared to those with no retinopathy, those with mild and moderate/severe retinopathy, respectively, had 81% (hazard ratio [HR] 1.81, 95% CI 1.29–2.55) and 314% (HR 4.14, 95% CI 1.77–9.69) increased risks of all-cause mortality. CONCLUSION. In this nationally representative sample of adults, those with mild or moderate/severe retinopathy were at increased risk of all-cause mortality.
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spelling pubmed-59512382019-05-01 Retinopathy and Mortality Frith, Emily Loprinzi, Paul D. Diabetes Spectr Feature Articles OBJECTIVE. We evaluated the specific association between retinopathy and all-cause mortality among a national sample of the broader U.S. adult population. METHODS. Data from the 2005–2008 National Health and Nutrition Examination Survey were used to identify 4,777 adults with complete data regarding screening for nonproliferative retinopathy using Early Treatment Diabetic Retinopathy Study grading criteria, as well as objective retinal imaging assessments using the Canon Non-Mydriatic Retinal Camera CR6-45NM. Participants were not included if they had been diagnosed with coronary artery disease, congestive heart failure, heart attack, or stroke at the baseline assessment. RESULTS. Both mild and moderate/severe retinopathy were associated with increased all-cause mortality risk in unadjusted and adjusted models. In the adjusted model, and when compared to those with no retinopathy, those with mild and moderate/severe retinopathy, respectively, had 81% (hazard ratio [HR] 1.81, 95% CI 1.29–2.55) and 314% (HR 4.14, 95% CI 1.77–9.69) increased risks of all-cause mortality. CONCLUSION. In this nationally representative sample of adults, those with mild or moderate/severe retinopathy were at increased risk of all-cause mortality. American Diabetes Association 2018-05 /pmc/articles/PMC5951238/ /pubmed/29773939 http://dx.doi.org/10.2337/ds17-0010 Text en © 2018 by the American Diabetes Association. Readers may use this article as long as the work is properly cited, the use is educational and not for profit, and the work is not altered. See http://creativecommons.org/licenses/by-nc-nd/3.0 for details.
spellingShingle Feature Articles
Frith, Emily
Loprinzi, Paul D.
Retinopathy and Mortality
title Retinopathy and Mortality
title_full Retinopathy and Mortality
title_fullStr Retinopathy and Mortality
title_full_unstemmed Retinopathy and Mortality
title_short Retinopathy and Mortality
title_sort retinopathy and mortality
topic Feature Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5951238/
https://www.ncbi.nlm.nih.gov/pubmed/29773939
http://dx.doi.org/10.2337/ds17-0010
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