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Label-Free Electrochemical Detection of Vanillin through Low-Defect Graphene Electrodes Modified with Au Nanoparticles

Graphene is an excellent modifier for the surface modification of electrochemical electrodes due to its exceptional physical properties and, for the development of graphene-based chemical and biosensors, is usually coated on glassy carbon electrodes (GCEs) via drop casting. However, the ease of aggr...

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Detalles Bibliográficos
Autores principales: Gao, Jingyao, Yuan, Qilong, Ye, Chen, Guo, Pei, Du, Shiyu, Lai, Guosong, Yu, Aimin, Jiang, Nan, Fu, Li, Lin, Cheng-Te, Chee, Kuan W.A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5951335/
https://www.ncbi.nlm.nih.gov/pubmed/29587385
http://dx.doi.org/10.3390/ma11040489
Descripción
Sumario:Graphene is an excellent modifier for the surface modification of electrochemical electrodes due to its exceptional physical properties and, for the development of graphene-based chemical and biosensors, is usually coated on glassy carbon electrodes (GCEs) via drop casting. However, the ease of aggregation and high defect content of reduced graphene oxides degrade the electrical properties. Here, we fabricated low-defect graphene electrodes by catalytically thermal treatment of HPHT diamond substrate, followed by the electrodeposition of Au nanoparticles (AuNPs) with an average size of ≈60 nm on the electrode surface using cyclic voltammetry. The Au nanoparticle-decorated graphene electrodes show a wide linear response range to vanillin from 0.2 to 40 µM with a low limit of detection of 10 nM. This work demonstrates the potential applications of graphene-based hybrid electrodes for highly sensitive chemical detection.