Cargando…

Label-Free Electrochemical Detection of Vanillin through Low-Defect Graphene Electrodes Modified with Au Nanoparticles

Graphene is an excellent modifier for the surface modification of electrochemical electrodes due to its exceptional physical properties and, for the development of graphene-based chemical and biosensors, is usually coated on glassy carbon electrodes (GCEs) via drop casting. However, the ease of aggr...

Descripción completa

Detalles Bibliográficos
Autores principales: Gao, Jingyao, Yuan, Qilong, Ye, Chen, Guo, Pei, Du, Shiyu, Lai, Guosong, Yu, Aimin, Jiang, Nan, Fu, Li, Lin, Cheng-Te, Chee, Kuan W.A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5951335/
https://www.ncbi.nlm.nih.gov/pubmed/29587385
http://dx.doi.org/10.3390/ma11040489
_version_ 1783323005519134720
author Gao, Jingyao
Yuan, Qilong
Ye, Chen
Guo, Pei
Du, Shiyu
Lai, Guosong
Yu, Aimin
Jiang, Nan
Fu, Li
Lin, Cheng-Te
Chee, Kuan W.A.
author_facet Gao, Jingyao
Yuan, Qilong
Ye, Chen
Guo, Pei
Du, Shiyu
Lai, Guosong
Yu, Aimin
Jiang, Nan
Fu, Li
Lin, Cheng-Te
Chee, Kuan W.A.
author_sort Gao, Jingyao
collection PubMed
description Graphene is an excellent modifier for the surface modification of electrochemical electrodes due to its exceptional physical properties and, for the development of graphene-based chemical and biosensors, is usually coated on glassy carbon electrodes (GCEs) via drop casting. However, the ease of aggregation and high defect content of reduced graphene oxides degrade the electrical properties. Here, we fabricated low-defect graphene electrodes by catalytically thermal treatment of HPHT diamond substrate, followed by the electrodeposition of Au nanoparticles (AuNPs) with an average size of ≈60 nm on the electrode surface using cyclic voltammetry. The Au nanoparticle-decorated graphene electrodes show a wide linear response range to vanillin from 0.2 to 40 µM with a low limit of detection of 10 nM. This work demonstrates the potential applications of graphene-based hybrid electrodes for highly sensitive chemical detection.
format Online
Article
Text
id pubmed-5951335
institution National Center for Biotechnology Information
language English
publishDate 2018
publisher MDPI
record_format MEDLINE/PubMed
spelling pubmed-59513352018-05-15 Label-Free Electrochemical Detection of Vanillin through Low-Defect Graphene Electrodes Modified with Au Nanoparticles Gao, Jingyao Yuan, Qilong Ye, Chen Guo, Pei Du, Shiyu Lai, Guosong Yu, Aimin Jiang, Nan Fu, Li Lin, Cheng-Te Chee, Kuan W.A. Materials (Basel) Communication Graphene is an excellent modifier for the surface modification of electrochemical electrodes due to its exceptional physical properties and, for the development of graphene-based chemical and biosensors, is usually coated on glassy carbon electrodes (GCEs) via drop casting. However, the ease of aggregation and high defect content of reduced graphene oxides degrade the electrical properties. Here, we fabricated low-defect graphene electrodes by catalytically thermal treatment of HPHT diamond substrate, followed by the electrodeposition of Au nanoparticles (AuNPs) with an average size of ≈60 nm on the electrode surface using cyclic voltammetry. The Au nanoparticle-decorated graphene electrodes show a wide linear response range to vanillin from 0.2 to 40 µM with a low limit of detection of 10 nM. This work demonstrates the potential applications of graphene-based hybrid electrodes for highly sensitive chemical detection. MDPI 2018-03-25 /pmc/articles/PMC5951335/ /pubmed/29587385 http://dx.doi.org/10.3390/ma11040489 Text en © 2018 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Communication
Gao, Jingyao
Yuan, Qilong
Ye, Chen
Guo, Pei
Du, Shiyu
Lai, Guosong
Yu, Aimin
Jiang, Nan
Fu, Li
Lin, Cheng-Te
Chee, Kuan W.A.
Label-Free Electrochemical Detection of Vanillin through Low-Defect Graphene Electrodes Modified with Au Nanoparticles
title Label-Free Electrochemical Detection of Vanillin through Low-Defect Graphene Electrodes Modified with Au Nanoparticles
title_full Label-Free Electrochemical Detection of Vanillin through Low-Defect Graphene Electrodes Modified with Au Nanoparticles
title_fullStr Label-Free Electrochemical Detection of Vanillin through Low-Defect Graphene Electrodes Modified with Au Nanoparticles
title_full_unstemmed Label-Free Electrochemical Detection of Vanillin through Low-Defect Graphene Electrodes Modified with Au Nanoparticles
title_short Label-Free Electrochemical Detection of Vanillin through Low-Defect Graphene Electrodes Modified with Au Nanoparticles
title_sort label-free electrochemical detection of vanillin through low-defect graphene electrodes modified with au nanoparticles
topic Communication
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5951335/
https://www.ncbi.nlm.nih.gov/pubmed/29587385
http://dx.doi.org/10.3390/ma11040489
work_keys_str_mv AT gaojingyao labelfreeelectrochemicaldetectionofvanillinthroughlowdefectgrapheneelectrodesmodifiedwithaunanoparticles
AT yuanqilong labelfreeelectrochemicaldetectionofvanillinthroughlowdefectgrapheneelectrodesmodifiedwithaunanoparticles
AT yechen labelfreeelectrochemicaldetectionofvanillinthroughlowdefectgrapheneelectrodesmodifiedwithaunanoparticles
AT guopei labelfreeelectrochemicaldetectionofvanillinthroughlowdefectgrapheneelectrodesmodifiedwithaunanoparticles
AT dushiyu labelfreeelectrochemicaldetectionofvanillinthroughlowdefectgrapheneelectrodesmodifiedwithaunanoparticles
AT laiguosong labelfreeelectrochemicaldetectionofvanillinthroughlowdefectgrapheneelectrodesmodifiedwithaunanoparticles
AT yuaimin labelfreeelectrochemicaldetectionofvanillinthroughlowdefectgrapheneelectrodesmodifiedwithaunanoparticles
AT jiangnan labelfreeelectrochemicaldetectionofvanillinthroughlowdefectgrapheneelectrodesmodifiedwithaunanoparticles
AT fuli labelfreeelectrochemicaldetectionofvanillinthroughlowdefectgrapheneelectrodesmodifiedwithaunanoparticles
AT linchengte labelfreeelectrochemicaldetectionofvanillinthroughlowdefectgrapheneelectrodesmodifiedwithaunanoparticles
AT cheekuanwa labelfreeelectrochemicaldetectionofvanillinthroughlowdefectgrapheneelectrodesmodifiedwithaunanoparticles