Cargando…
Label-Free Electrochemical Detection of Vanillin through Low-Defect Graphene Electrodes Modified with Au Nanoparticles
Graphene is an excellent modifier for the surface modification of electrochemical electrodes due to its exceptional physical properties and, for the development of graphene-based chemical and biosensors, is usually coated on glassy carbon electrodes (GCEs) via drop casting. However, the ease of aggr...
Autores principales: | , , , , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2018
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5951335/ https://www.ncbi.nlm.nih.gov/pubmed/29587385 http://dx.doi.org/10.3390/ma11040489 |
_version_ | 1783323005519134720 |
---|---|
author | Gao, Jingyao Yuan, Qilong Ye, Chen Guo, Pei Du, Shiyu Lai, Guosong Yu, Aimin Jiang, Nan Fu, Li Lin, Cheng-Te Chee, Kuan W.A. |
author_facet | Gao, Jingyao Yuan, Qilong Ye, Chen Guo, Pei Du, Shiyu Lai, Guosong Yu, Aimin Jiang, Nan Fu, Li Lin, Cheng-Te Chee, Kuan W.A. |
author_sort | Gao, Jingyao |
collection | PubMed |
description | Graphene is an excellent modifier for the surface modification of electrochemical electrodes due to its exceptional physical properties and, for the development of graphene-based chemical and biosensors, is usually coated on glassy carbon electrodes (GCEs) via drop casting. However, the ease of aggregation and high defect content of reduced graphene oxides degrade the electrical properties. Here, we fabricated low-defect graphene electrodes by catalytically thermal treatment of HPHT diamond substrate, followed by the electrodeposition of Au nanoparticles (AuNPs) with an average size of ≈60 nm on the electrode surface using cyclic voltammetry. The Au nanoparticle-decorated graphene electrodes show a wide linear response range to vanillin from 0.2 to 40 µM with a low limit of detection of 10 nM. This work demonstrates the potential applications of graphene-based hybrid electrodes for highly sensitive chemical detection. |
format | Online Article Text |
id | pubmed-5951335 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2018 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-59513352018-05-15 Label-Free Electrochemical Detection of Vanillin through Low-Defect Graphene Electrodes Modified with Au Nanoparticles Gao, Jingyao Yuan, Qilong Ye, Chen Guo, Pei Du, Shiyu Lai, Guosong Yu, Aimin Jiang, Nan Fu, Li Lin, Cheng-Te Chee, Kuan W.A. Materials (Basel) Communication Graphene is an excellent modifier for the surface modification of electrochemical electrodes due to its exceptional physical properties and, for the development of graphene-based chemical and biosensors, is usually coated on glassy carbon electrodes (GCEs) via drop casting. However, the ease of aggregation and high defect content of reduced graphene oxides degrade the electrical properties. Here, we fabricated low-defect graphene electrodes by catalytically thermal treatment of HPHT diamond substrate, followed by the electrodeposition of Au nanoparticles (AuNPs) with an average size of ≈60 nm on the electrode surface using cyclic voltammetry. The Au nanoparticle-decorated graphene electrodes show a wide linear response range to vanillin from 0.2 to 40 µM with a low limit of detection of 10 nM. This work demonstrates the potential applications of graphene-based hybrid electrodes for highly sensitive chemical detection. MDPI 2018-03-25 /pmc/articles/PMC5951335/ /pubmed/29587385 http://dx.doi.org/10.3390/ma11040489 Text en © 2018 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Communication Gao, Jingyao Yuan, Qilong Ye, Chen Guo, Pei Du, Shiyu Lai, Guosong Yu, Aimin Jiang, Nan Fu, Li Lin, Cheng-Te Chee, Kuan W.A. Label-Free Electrochemical Detection of Vanillin through Low-Defect Graphene Electrodes Modified with Au Nanoparticles |
title | Label-Free Electrochemical Detection of Vanillin through Low-Defect Graphene Electrodes Modified with Au Nanoparticles |
title_full | Label-Free Electrochemical Detection of Vanillin through Low-Defect Graphene Electrodes Modified with Au Nanoparticles |
title_fullStr | Label-Free Electrochemical Detection of Vanillin through Low-Defect Graphene Electrodes Modified with Au Nanoparticles |
title_full_unstemmed | Label-Free Electrochemical Detection of Vanillin through Low-Defect Graphene Electrodes Modified with Au Nanoparticles |
title_short | Label-Free Electrochemical Detection of Vanillin through Low-Defect Graphene Electrodes Modified with Au Nanoparticles |
title_sort | label-free electrochemical detection of vanillin through low-defect graphene electrodes modified with au nanoparticles |
topic | Communication |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5951335/ https://www.ncbi.nlm.nih.gov/pubmed/29587385 http://dx.doi.org/10.3390/ma11040489 |
work_keys_str_mv | AT gaojingyao labelfreeelectrochemicaldetectionofvanillinthroughlowdefectgrapheneelectrodesmodifiedwithaunanoparticles AT yuanqilong labelfreeelectrochemicaldetectionofvanillinthroughlowdefectgrapheneelectrodesmodifiedwithaunanoparticles AT yechen labelfreeelectrochemicaldetectionofvanillinthroughlowdefectgrapheneelectrodesmodifiedwithaunanoparticles AT guopei labelfreeelectrochemicaldetectionofvanillinthroughlowdefectgrapheneelectrodesmodifiedwithaunanoparticles AT dushiyu labelfreeelectrochemicaldetectionofvanillinthroughlowdefectgrapheneelectrodesmodifiedwithaunanoparticles AT laiguosong labelfreeelectrochemicaldetectionofvanillinthroughlowdefectgrapheneelectrodesmodifiedwithaunanoparticles AT yuaimin labelfreeelectrochemicaldetectionofvanillinthroughlowdefectgrapheneelectrodesmodifiedwithaunanoparticles AT jiangnan labelfreeelectrochemicaldetectionofvanillinthroughlowdefectgrapheneelectrodesmodifiedwithaunanoparticles AT fuli labelfreeelectrochemicaldetectionofvanillinthroughlowdefectgrapheneelectrodesmodifiedwithaunanoparticles AT linchengte labelfreeelectrochemicaldetectionofvanillinthroughlowdefectgrapheneelectrodesmodifiedwithaunanoparticles AT cheekuanwa labelfreeelectrochemicaldetectionofvanillinthroughlowdefectgrapheneelectrodesmodifiedwithaunanoparticles |