BRCA1 and BRCA2 tumor suppressors in neural crest cells are essential for craniofacial bone development

Craniofacial abnormalities, including facial skeletal defects, comprise approximately one-third of all birth defects in humans. Since most bones in the face derive from cranial neural crest cells (CNCCs), which are multipotent stem cells, craniofacial bone disorders are largely attributed to defects...

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Detalles Bibliográficos
Autores principales: Kitami, Kohei, Kitami, Megumi, Kaku, Masaru, Wang, Bin, Komatsu, Yoshihiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5951594/
https://www.ncbi.nlm.nih.gov/pubmed/29718910
http://dx.doi.org/10.1371/journal.pgen.1007340

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5951594/
https://www.ncbi.nlm.nih.gov/pubmed/29718910
http://dx.doi.org/10.1371/journal.pgen.1007340

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