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The extent of liver injury determines hepatocyte fate toward senescence or cancer
It is well known that induction of hepatocyte senescence could inhibit the development of hepatocellular carcinoma (HCC). Until now, it is still unclear how the degree of liver injury dictates hepatocyte senescence and carcinogenesis. In this study, we investigated whether the severity of injury det...
Autores principales: | Wang, Chao, Chen, Wen-Jian, Wu, Ying-Fu, You, Pu, Zheng, Shang-Yong, Liu, Chang-Cheng, Xiang, Dao, Wang, Min-Jun, Cai, Yong-Chao, Zhao, Qing-Hui, Borjigin, Uyunbilig, Liu, Wei, Xiong, Wu-Jun, Wangensteen, Kirk J., Wang, Xin, Liu, Zhong-Min, He, Zhi-Ying |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5951829/ https://www.ncbi.nlm.nih.gov/pubmed/29760381 http://dx.doi.org/10.1038/s41419-018-0622-x |
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