Parental haplotype-specific single-cell transcriptomics reveal incomplete epigenetic reprogramming in human female germ cells

In contrast to mouse, human female germ cells develop asynchronously. Germ cells transition to meiosis, erase genomic imprints, and reactivate the X chromosome. It is unknown if these events all appear asynchronously, and how they relate to each other. Here we combine exome sequencing of human fetal...

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Detalles Bibliográficos
Autores principales: Vértesy, Ábel, Arindrarto, Wibowo, Roost, Matthias S., Reinius, Björn, Torrens-Juaneda, Vanessa, Bialecka, Monika, Moustakas, Ioannis, Ariyurek, Yavuz, Kuijk, Ewart, Mei, Hailiang, Sandberg, Rickard, van Oudenaarden, Alexander, Chuva de Sousa Lopes, Susana M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5951918/
https://www.ncbi.nlm.nih.gov/pubmed/29760424
http://dx.doi.org/10.1038/s41467-018-04215-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5951918/
https://www.ncbi.nlm.nih.gov/pubmed/29760424
http://dx.doi.org/10.1038/s41467-018-04215-7

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