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Hierarchical mechanism of amino acid sensing by the T-box riboswitch
In Gram-positive bacteria, T-box riboswitches control gene expression to maintain the cellular pools of aminoacylated tRNAs essential for protein biosynthesis. Co-transcriptional binding of an uncharged tRNA to the riboswitch stabilizes an antiterminator, allowing transcription read-through, whereas...
Autores principales: | Suddala, Krishna C., Cabello-Villegas, Javier, Michnicka, Malgorzata, Marshall, Collin, Nikonowicz, Edward P., Walter, Nils G. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5951919/ https://www.ncbi.nlm.nih.gov/pubmed/29760498 http://dx.doi.org/10.1038/s41467-018-04305-6 |
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