A new inhibitor of glucose-6-phosphate dehydrogenase blocks pentose phosphate pathway and suppresses malignant proliferation and metastasis in vivo

Pentose phosphate pathway (PPP) is a major glucose metabolism pathway, which has a fundamental role in cancer growth and metastasis. Even though PPP blockade has been pointed out as a very promising strategy against cancer, effective anti-PPP agents are not still available in the clinical setting. H...

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Detalles Bibliográficos
Autores principales: Mele, Luigi, Paino, Francesca, Papaccio, Federica, Regad, Tarik, Boocock, David, Stiuso, Paola, Lombardi, Angela, Liccardo, Davide, Aquino, Gabriella, Barbieri, Antonio, Arra, Claudio, Coveney, Clare, La Noce, Marcella, Papaccio, Gianpaolo, Caraglia, Michele, Tirino, Virginia, Desiderio, Vincenzo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5951921/
https://www.ncbi.nlm.nih.gov/pubmed/29760380
http://dx.doi.org/10.1038/s41419-018-0635-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5951921/
https://www.ncbi.nlm.nih.gov/pubmed/29760380
http://dx.doi.org/10.1038/s41419-018-0635-5

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