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Interleukin-2-Inducible T-Cell Kinase Deficiency—New Patients, New Insight?

Patients with primary immunodeficiency can be prone to severe Epstein–Barr virus (EBV) associated immune dysregulation. Individuals with mutations in the interleukin-2-inducible T-cell kinase (ITK) gene experience Hodgkin and non-Hodgkin lymphoma, EBV lymphoproliferative disease, hemophagocytic lymp...

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Detalles Bibliográficos
Autores principales: Ghosh, Sujal, Drexler, Ingo, Bhatia, Sanil, Adler, Heiko, Gennery, Andrew R., Borkhardt, Arndt
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5951928/
https://www.ncbi.nlm.nih.gov/pubmed/29867957
http://dx.doi.org/10.3389/fimmu.2018.00979