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The novel 19q13 KRAB zinc-finger tumour suppressor ZNF382 is frequently methylated in oesophageal squamous cell carcinoma and antagonises Wnt/β-catenin signalling

Zinc finger proteins (ZFPs) are the largest transcription factor family in mammals. About one-third of ZFPs are Krüppel-associated box domain (KRAB)-ZFPs and involved in the regulation of cell differentiation/proliferation/apoptosis and neoplastic transformation. We recently identified ZNF382 as a n...

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Detalles Bibliográficos
Autores principales: Zhang, Chong, Xiang, Tingxiu, Li, Shuman, Ye, Lin, Feng, Yixiao, Pei, Lijiao, Li, Lili, Wang, Xiangyu, Sun, Ran, Ren, Guosheng, Tao, Qian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5951945/
https://www.ncbi.nlm.nih.gov/pubmed/29760376
http://dx.doi.org/10.1038/s41419-018-0604-z