Small Molecule Modulators of RING-Type E3 Ligases: MDM and Cullin Families as Targets

Ubiquitin–proteasome system (UPS) is a primary signaling pathway for regulation of intracellular protein levels. E3 ubiquitin ligases, substrate-specific members of the UPS, represent highly attractive protein targets for drug discovery. The importance of E3 ligases as prospective targets for small...

Descripción completa

Detalles Bibliográficos
Autores principales: Bulatov, Emil, Zagidullin, Almaz, Valiullina, Aygul, Sayarova, Regina, Rizvanov, Albert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5951978/
https://www.ncbi.nlm.nih.gov/pubmed/29867461
http://dx.doi.org/10.3389/fphar.2018.00450

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5951978/
https://www.ncbi.nlm.nih.gov/pubmed/29867461
http://dx.doi.org/10.3389/fphar.2018.00450

Ejemplares similares