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Metformin Mitigates Fibrosis and Glucose Intolerance Induced by Doxorubicin in Subcutaneous Adipose Tissue

Doxorubicin (DX) is a chemotherapeutic drug that is used in clinical practice that promotes deleterious side effects in non-tumor tissues such as adipose tissue. We showed that DX leads to extensive damage in adipose tissue via a disruption in 5′-adenosine monophosphate-activated protein kinase (AMP...

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Detalles Bibliográficos
Autores principales:	Biondo, Luana A., Batatinha, Helena A., Souza, Camila O., Teixeira, Alexandre A. S., Silveira, Loreana S., Alonso-Vale, Maria I., Oyama, Lila M., Alves, Michele J., Seelaender, Marilia, Neto, José C. R.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2018
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5952005/ https://www.ncbi.nlm.nih.gov/pubmed/29867463 http://dx.doi.org/10.3389/fphar.2018.00452

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