Oral immunization with rotavirus VP7-CTB fusion expressed in transgenic Arabidopsis thaliana induces antigen-specific IgA and IgG and passive protection in mice

Human rotavirus (HRV) is the primary cause of severe gastroenteritis in children. However, there is currently no protective virus for rotavirus available. In the present study, an HRVVP7-cholera toxin B subunit (CTB) fusion protein was expressed in Arabidopsis thaliana. To determine the adjuvant eff...

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Detalles Bibliográficos
Autores principales: Li, Yuxian, Guan, Lili, Liu, Xiuming, Liu, Weican, Yang, Jing, Zhang, Xiaomei, Wang, Fawei, Guo, Yongxin, Li, Haiyan, Li, Xiaokun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2018
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5952079/
https://www.ncbi.nlm.nih.gov/pubmed/29805507
http://dx.doi.org/10.3892/etm.2018.6003

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