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H5N1 Influenza A Virus PB1-F2 Relieves HAX-1-Mediated Restriction of Avian Virus Polymerase PA in Human Lung Cells

Highly pathogenic influenza A viruses (IAV) from avian hosts were first reported to directly infect humans 20 years ago. However, such infections are rare events, and our understanding of factors promoting or restricting zoonotic transmission is still limited. One accessory protein of IAV, PB1-F2, w...

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Detalles Bibliográficos
Autores principales: Mazel-Sanchez, B., Boal-Carvalho, I., Silva, F., Dijkman, R., Schmolke, M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5952157/
https://www.ncbi.nlm.nih.gov/pubmed/29563290
http://dx.doi.org/10.1128/JVI.00425-18

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