Identification of a Mycothiol-Dependent Nitroreductase from Mycobacterium tuberculosis

[Image: see text] The success of Mycobacterium tuberculosis (Mtb) as a pathogen depends on the redundant and complex mechanisms it has evolved for resisting nitrosative and oxidative stresses inflicted by host immunity. Improving our understanding of these defense pathways can reveal vulnerable poin...

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Detalles Bibliográficos
Autores principales: Negri, Ana, Javidnia, Prisca, Mu, Ran, Zhang, Xiaojie, Vendome, Jeremie, Gold, Ben, Roberts, Julia, Barman, Dipti, Ioerger, Thomas, Sacchettini, James C., Jiang, Xiuju, Burns-Huang, Kristin, Warrier, Thulasi, Ling, Yan, Warren, J. David, Oren, Deena A., Beuming, Thijs, Wang, Hongyao, Wu, Jie, Li, Haitao, Rhee, Kyu Y., Nathan, Carl F., Liu, Gang, Somersan-Karakaya, Selin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2018
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5952258/
https://www.ncbi.nlm.nih.gov/pubmed/29465985
http://dx.doi.org/10.1021/acsinfecdis.7b00111

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