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Catalytic activation of a single C–F bond in trifluoromethyl arenes
Synthetic methods for the direct transformation of ArCF(3) to ArCF(2)R would enable efficient diversification of trifluoromethyl arenes and would be of great utility in medicinal chemistry. Unfortunately, the development of such methods has been hampered by the fundamental properties of C–F bonds, w...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Royal Society of Chemistry
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5952311/ https://www.ncbi.nlm.nih.gov/pubmed/29861997 http://dx.doi.org/10.1039/c5sc03415a |