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Apoptosis-Inducing Factor (AIF) in Physiology and Disease: The Tale of a Repented Natural Born Killer

Apoptosis-inducing factor (AIF) is a mitochondrial oxidoreductase that contributes to cell death programmes and participates in the assembly of the respiratory chain. Importantly, AIF deficiency leads to severe mitochondrial dysfunction, causing muscle atrophy and neurodegeneration in model organism...

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Detalles Bibliográficos
Autores principales: Bano, Daniele, Prehn, Jochen H.M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5952348/
https://www.ncbi.nlm.nih.gov/pubmed/29605508
http://dx.doi.org/10.1016/j.ebiom.2018.03.016