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Metformin attenuates triglyceride accumulation in HepG2 cells through decreasing stearyl-coenzyme A desaturase 1 expression

BACKGROUND: The prevalence of nonalcoholic fatty liver disease (NAFLD) has increased worldwide. Metformin decreases triglyceride (TG) accumulation in hepatocytes in vivo and in vitro. Stearyl-coenzyme A desaturase 1 (SCD1) knockout mice also show decreased liver TG accumulation; however, whether SCD...

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Detalles Bibliográficos
Autores principales:	Zhu, Xiaopeng, Yan, Hongmei, Xia, Mingfeng, Chang, Xinxia, Xu, Xi, Wang, Liu, Sun, Xiaoyang, Lu, Yan, Bian, Hua, Li, Xiaoying, Gao, Xin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2018
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5952420/ https://www.ncbi.nlm.nih.gov/pubmed/29759071 http://dx.doi.org/10.1186/s12944-018-0762-0

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