Deletion of Tsc2 in Nociceptors Reduces Target Innervation, Ion Channel Expression, and Sensitivity to Heat

The mechanistic target of rapamycin complex 1 (mTORC1) is known to regulate cellular growth pathways, and its genetic activation is sufficient to enhance regenerative axon growth following injury to the central or peripheral nervous systems. However, excess mTORC1 activation may promote innervation...

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Detalles Bibliográficos
Autores principales: Carlin, Dan, Golden, Judith P., Mogha, Amit, Samineni, Vijay K., Monk, Kelly R., Gereau, Robert W., Cavalli, Valeria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Society for Neuroscience 2018
Materias:
New Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5952427/
https://www.ncbi.nlm.nih.gov/pubmed/29766046
http://dx.doi.org/10.1523/ENEURO.0436-17.2018

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5952427/
https://www.ncbi.nlm.nih.gov/pubmed/29766046
http://dx.doi.org/10.1523/ENEURO.0436-17.2018

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