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Astragaloside Inhibits Hepatic Fibrosis by Modulation of TGF-β1/Smad Signaling Pathway

Activation of HSC is a pivotal step in hepatic fibrosis. In the activation of HSC, the TGF-β1 plays a key role that can promote the occurrence of hepatic fibrosis by combining with Smad proteins. Astragaloside is the main active component extracted from Radix Astragali that has the effect of antioxi...

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Detalles Bibliográficos
Autores principales: Yuan, Xingxing, Gong, Zhiqiang, Wang, Bingyu, Guo, Xueying, Yang, Lei, Li, Dandan, Zhang, Yali
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5952439/
https://www.ncbi.nlm.nih.gov/pubmed/29853950
http://dx.doi.org/10.1155/2018/3231647

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