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Minimally Invasive Treatment of Sporadic Burkitt's Lymphoma Causing Ileocaecal Invagination
INTRODUCTION: Primary NHL (non-Hodgkin lymphoma) of the colon represents only 0.2% to 1.2% of all colonic malignancies. Burkitt's lymphoma (BL) is usually a disease reported in children and young people, most of them associated with EBV or HIV infection. We describe a rare case of intestinal ob...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Hindawi
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5952441/ https://www.ncbi.nlm.nih.gov/pubmed/29854542 http://dx.doi.org/10.1155/2018/6265182 |
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author | Panaccio, Paolo Fiordaliso, Michele Testa, Domenica Mazzola, Lorenzo Battilana, Mariangela Cotellese, Roberto Selvaggi, Federico |
author_facet | Panaccio, Paolo Fiordaliso, Michele Testa, Domenica Mazzola, Lorenzo Battilana, Mariangela Cotellese, Roberto Selvaggi, Federico |
author_sort | Panaccio, Paolo |
collection | PubMed |
description | INTRODUCTION: Primary NHL (non-Hodgkin lymphoma) of the colon represents only 0.2% to 1.2% of all colonic malignancies. Burkitt's lymphoma (BL) is usually a disease reported in children and young people, most of them associated with EBV or HIV infection. We describe a rare case of intestinal obstruction due to sporadic Burkitt's lymphoma causing ileocaecal invagination explaining our experience Methods. A 31-year-old man presented with diffuse colic pain and weight loss. Clinical examination revealed an abdominal distension with pain in the right iliac fossa. Colonoscopy documented a caecal large lesion with ulcerated mucosa. Computed tomography (CT) have shown a 60 × 50 mm right colic parietal lesion with signs of ileocolic intussusception. RESULTS: Laparoscopic right hemicolectomy was performed. Postoperative period was uneventful. CD20+ high-grade B-cell Burkitt's lymphoma was confirmed by immunohistochemistry (CD20+, CD79+, and CD10+) and FISH test (t (8;14) (q24; q32). The patient was subsequently treated with adjuvant combination chemotherapy (Hyper-CVAD) and is alive and disease-free at 8 months follow-up. DISCUSSION: Adult sporadic Burkitt's lymphoma (BL) causing intestinal obstruction due to ileocaecal intussusception is an extremely rare occurrence and a diagnostic dilemma. Despite the surgical approach is selected based on patient's conditions and surgeon's expertise, minimally invasive method could be preferred. |
format | Online Article Text |
id | pubmed-5952441 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2018 |
publisher | Hindawi |
record_format | MEDLINE/PubMed |
spelling | pubmed-59524412018-05-31 Minimally Invasive Treatment of Sporadic Burkitt's Lymphoma Causing Ileocaecal Invagination Panaccio, Paolo Fiordaliso, Michele Testa, Domenica Mazzola, Lorenzo Battilana, Mariangela Cotellese, Roberto Selvaggi, Federico Case Rep Surg Case Report INTRODUCTION: Primary NHL (non-Hodgkin lymphoma) of the colon represents only 0.2% to 1.2% of all colonic malignancies. Burkitt's lymphoma (BL) is usually a disease reported in children and young people, most of them associated with EBV or HIV infection. We describe a rare case of intestinal obstruction due to sporadic Burkitt's lymphoma causing ileocaecal invagination explaining our experience Methods. A 31-year-old man presented with diffuse colic pain and weight loss. Clinical examination revealed an abdominal distension with pain in the right iliac fossa. Colonoscopy documented a caecal large lesion with ulcerated mucosa. Computed tomography (CT) have shown a 60 × 50 mm right colic parietal lesion with signs of ileocolic intussusception. RESULTS: Laparoscopic right hemicolectomy was performed. Postoperative period was uneventful. CD20+ high-grade B-cell Burkitt's lymphoma was confirmed by immunohistochemistry (CD20+, CD79+, and CD10+) and FISH test (t (8;14) (q24; q32). The patient was subsequently treated with adjuvant combination chemotherapy (Hyper-CVAD) and is alive and disease-free at 8 months follow-up. DISCUSSION: Adult sporadic Burkitt's lymphoma (BL) causing intestinal obstruction due to ileocaecal intussusception is an extremely rare occurrence and a diagnostic dilemma. Despite the surgical approach is selected based on patient's conditions and surgeon's expertise, minimally invasive method could be preferred. Hindawi 2018-04-30 /pmc/articles/PMC5952441/ /pubmed/29854542 http://dx.doi.org/10.1155/2018/6265182 Text en Copyright © 2018 Paolo Panaccio et al. http://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Case Report Panaccio, Paolo Fiordaliso, Michele Testa, Domenica Mazzola, Lorenzo Battilana, Mariangela Cotellese, Roberto Selvaggi, Federico Minimally Invasive Treatment of Sporadic Burkitt's Lymphoma Causing Ileocaecal Invagination |
title | Minimally Invasive Treatment of Sporadic Burkitt's Lymphoma Causing Ileocaecal Invagination |
title_full | Minimally Invasive Treatment of Sporadic Burkitt's Lymphoma Causing Ileocaecal Invagination |
title_fullStr | Minimally Invasive Treatment of Sporadic Burkitt's Lymphoma Causing Ileocaecal Invagination |
title_full_unstemmed | Minimally Invasive Treatment of Sporadic Burkitt's Lymphoma Causing Ileocaecal Invagination |
title_short | Minimally Invasive Treatment of Sporadic Burkitt's Lymphoma Causing Ileocaecal Invagination |
title_sort | minimally invasive treatment of sporadic burkitt's lymphoma causing ileocaecal invagination |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5952441/ https://www.ncbi.nlm.nih.gov/pubmed/29854542 http://dx.doi.org/10.1155/2018/6265182 |
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