IDP-ASE: haplotyping and quantifying allele-specific expression at the gene and gene isoform level by hybrid sequencing

Allele-specific expression (ASE) is a fundamental problem in studying gene regulation and diploid transcriptome profiles, with two key challenges: (i) haplotyping and (ii) estimation of ASE at the gene isoform level. Existing ASE analysis methods are limited by a dependence on haplotyping from labor...

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Detalles Bibliográficos
Autores principales: Deonovic, Benjamin, Wang, Yunhao, Weirather, Jason, Wang, Xiu-Jie, Au, Kin Fai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Methods Online
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5952581/
https://www.ncbi.nlm.nih.gov/pubmed/27899656
http://dx.doi.org/10.1093/nar/gkw1076

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5952581/
https://www.ncbi.nlm.nih.gov/pubmed/27899656
http://dx.doi.org/10.1093/nar/gkw1076

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