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CHD7 Maintains Neural Stem Cell Quiescence and Prevents Premature Stem Cell Depletion in the Adult Hippocampus

Neural stem/progenitor cells (NSCs) in the hippocampus produce new neurons throughout adult life. NSCs are maintained in a state of reversible quiescence and the failure to maintain the quiescent state can result in the premature depletion of the stem cell pool. The epigenetic mechanisms that mainta...

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Detalles Bibliográficos
Autores principales: Jones, Kieran M., Sarić, Nemanja, Russell, John P., Andoniadou, Cynthia L., Scambler, Peter J., Basson, M. Albert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5952591/
https://www.ncbi.nlm.nih.gov/pubmed/25183173
http://dx.doi.org/10.1002/stem.1822