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High serum levels of pregenomic RNA reflect frequently failing reverse transcription in hepatitis B virus particles

BACKGROUND: Hepatocytes infected by hepatitis B virus (HBV) produce different HBV RNA species, including pregenomic RNA (pgRNA), which is reverse transcribed during replication. Particles containing HBV RNA are present in serum of infected individuals, and quantification of this HBV RNA could be cli...

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Detalles Bibliográficos
Autores principales:	Prakash, Kasthuri, Rydell, Gustaf E., Larsson, Simon B., Andersson, Maria, Norkrans, Gunnar, Norder, Heléne, Lindh, Magnus
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2018
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5952638/ https://www.ncbi.nlm.nih.gov/pubmed/29764511 http://dx.doi.org/10.1186/s12985-018-0994-7

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