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Mutational analysis of two residues in the DYRK homology box of the protein kinase DYRK1A

OBJECTIVE: Dual specificity tyrosine phosphorylation-regulated kinases (DYRK) contain a characteristic sequence motif (DYRK homology box, DH box) that is located N-terminal of the catalytic domain and supports the autophosphorylation of a conserved tyrosine during maturation of the catalytic domain....

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Detalles Bibliográficos
Autores principales: Widowati, Esti Wahyu, Bamberg-Lemper, Simone, Becker, Walter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5952693/
https://www.ncbi.nlm.nih.gov/pubmed/29764512
http://dx.doi.org/10.1186/s13104-018-3416-4